Recent research from West of Scotland Coronary Prevention Study found that 26% of the men had metabolic syndrome. They had 1.7 times the risk of a coronary heart disease event and 3.5 times the risk of developing diabetes during 4.9 years of follow-up. The risk increased as the number of metabolic abnormalities rose. Men with four or five features of metabolic syndrome had 3.7 times the risk of coronary heart disease and 24.5 times the risk of diabetes compared to those with no abnormalities. (Irish Medical Times August 22, 2003).

Syndrome X leads to coronary artery disease (angina and heart attacks). Cerebrovascular disease (stroke) Peripheral vascular disease.